Q 01/05

Roughly what share of dementia cases does Alzheimer's disease account for?

A) 10 to 20 percent

B) 30 to 40 percent

C) 60 to 70 percent

D) 95 to 99 percent

Answer · why

C) 60 to 70 percent

That makes it by far the most common cause of dementia.

Q 02/05

After whom is Alzheimer's disease named?

A) A Swiss neurologist

B) A Dutch pharmacist

C) An Austrian surgeon

D) A German psychiatrist and pathologist

Answer · why

D) A German psychiatrist and pathologist

Alois Alzheimer first reported the case publicly in 1906.

Q 03/05

Which region of the brain, associated with memory, does the disease target first?

A) The cerebellum

B) The brainstem

C) The hippocampus

D) The occipital lobe

Answer · why

C) The hippocampus

That is why the first symptoms are usually problems with learning and memory.

Q 04/05

What two kinds of malformed protein deposit characterise the disease in the cerebral cortex?

A) Lewy bodies and prions

B) Keratin fibres and collagen knots

C) Fibrin clots and lipofuscin

D) Amyloid plaques and neurofibrillary tangles

Answer · why

D) Amyloid plaques and neurofibrillary tangles

Amyloid beta builds up outside cells and tau protein inside them.

Q 05/05

Which protein forms the neurofibrillary tangles inside neurons?

A) Tau

B) Insulin

C) Myelin

D) Actin

Answer · why

A) Tau

The tau hypothesis and the amyloid hypothesis are the two leading explanations of the disease's origin.