50 free Powerpuff Girls trivia questions with answers — entertainment quiz, new questions added Aug 2026.
40 free Powerpuff Girls trivia questions with answers. The Powerpuff Girls ran on Cartoon Network from 1998 to 2005 and has never really gone away, thanks to a movie, a Japanese anime, a 2016 reboot and a fourth sister nobody asked for. This quiz covers the original show in depth: the girls' powers and personalities, Professor Utonium and Chemical X, the villains from Mojo Jojo and Him to Fuzzy Lumpkins and the Amoeba Boys, the voice cast, and how Craig McCracken's student film about the 'Whoopass Girls' became a hit. There are also questions on the 2002 movie, Powerpuff Girls Z, the 2016 reboot, Bliss, and the cancelled live-action series, so it works for kids who grew up on reruns and adults who watched it the first time round. Every answer is checked against Wikipedia and cited on the question, so you can see where each fact comes from.
30 of 50 questions with answers and explanations. Play the quiz
Q 01Who created The Powerpuff Girls?
Craig McCracken
He went on to make Foster's Home for Imaginary Friends and Wander Over Yonder.
Q 02What was the name of McCracken's CalArts student film that first featured the three girls?
Whoopass Stew!
Cartoon Network would not let him market a show with the word 'ass', so friends came up with 'Powerpuff'.
Q 03In the original student film, what gave the girls their powers before the network made McCracken change it?
A can of Whoopass
The 1966 Batman TV series was the inspiration for the superhero parody.
Q 04Professor Utonium made the girls from sugar, spice, everything nice and an accidental splash of what?
Chemical X
The same accident turned his lab assistant, a chimp named Jojo, into the super-intelligent Mojo Jojo.
Q 05In which fictional city do the Powerpuff Girls live?
Townsville
The Mayor calls them on the Powerpuff hotline whenever there is trouble.
Q 06What is Bubbles' signature colour?
Blue
Cartoon Network executives once suggested renaming the girls Pink, Blue and Green because they could not tell them apart.
Q 07Which ingredient is Buttercup's 'personality ingredient'?
Spice
McCracken originally wanted to call her Bud until a friend suggested Buttercup.
Q 08What is Buttercup's one unique power in the original series?
Curling her tongue
Bubbles can understand animals, and Blossom has ice breath.
Q 09Bubbles can understand various languages, including the language of what?
Animals
She is the 'sugar' of the trio and cries a lot, but she can hold her own in a fight.
Q 10How old are the girls?
Five
They attend Pokey Oaks Kindergarten, taught by Ms. Keane.
Q 11What is the name of the kindergarten the girls attend?
Pokey Oaks
Ms. Keane is named after Margaret Keane, the big-eyed-children painter whose work inspired the girls' design.
Q 12Which character's face is never shown on screen?
Sara Bellum
McCracken described her as 'the typical hot assistant, though her best feature is her brain'.
Q 13Mojo Jojo is what kind of animal?
A chimpanzee
He lives in an observatory on top of a dormant volcano in Townsville Central Park.
Q 14Which comic-book reference inspired Mojo Jojo's repetitive, redundant way of speaking?
Q 21Which villain was left out of the 2016 reboot because of concerns over her sexualised design?
Sedusa
She is a Gorgon-like seductress with prehensile hair, voiced by Jennifer Hale.
Q 22Who voiced both the Mayor and the Narrator in the original series?
Tom Kenny
He was voicing SpongeBob SquarePants at the same time.
Q 23Which actor voiced both Professor Utonium and Him?
Tom Kane
He also voiced the Talking Dog, whose pain is a running gag no one ever notices.
Q 24Who voiced Mojo Jojo?
The DC Superdictionary
His rhythms were also modelled on the English dub of Speed Racer.
Q 15The demonic villain Him was designed as a homage to which character from Yellow Submarine?
The Chief Blue Meanie
The staff set out to make Him 'as scary as possible'.
Q 16Fuzzy Lumpkins is described as what kind of monster?
A pink furry hillbilly
He starred in the very first short, 'Meat Fuzzy Lumpkins', in 1995.
Q 17The Rowdyruff Boys were made by Mojo Jojo from snips, snails, a puppy dog tail and what?
Radioactive toilet water
They are Brick, Boomer and Butch, and were first destroyed when the girls kissed them.
Q 18How did the girls originally defeat the Rowdyruff Boys?
By kissing them
Brick is voiced by Rob Paulsen, better known as Yakko and Pinky.
Q 19The Amoeba Boys are a trio of single-celled gangsters with accents from where?
Brooklyn
They are called Bossman, Junior and Slim, and are too incompetent to be taken seriously.
Q 20Which member of the Gangreen Gang joined Gorillaz as their bassist in 2018?
Ace
The Gang lives in a shack in Townsville's junkyard and has no superpowers at all.
Roger L. Jackson
Jackson is also the voice of Ghostface in the Scream films.
Q 25Tara Strong, the voice of Bubbles, was born in which city?
Toronto
She also voices Twilight Sparkle, Timmy Turner and Ben Tennyson.
Q 26E. G. Daily, the voice of Buttercup, also voices which Rugrats baby?
Tommy Pickles
On screen she played Dottie in Pee-wee's Big Adventure.
Q 27Which actress voiced the red-haired leader of the trio in the original series?
Cathy Cavadini
McCracken said her voice had 'sincerity and strength and cuteness' and called her perfect for the part.
Q 28On what date did The Powerpuff Girls premiere on Cartoon Network?
November 18, 1998
It was the highest-rated premiere of any Cartoon Network series at that time.
Q 29How many seasons did the original series run?
Six
McCracken left after four to concentrate on Foster's Home for Imaginary Friends.
Q 30The first Powerpuff Girls short premiered in 1995 during an episode of which show?
Space Ghost Coast to Coast
It was part of the What a Cartoon! / World Premiere Toons programme.