140 free House M.D. trivia questions with answers — entertainment quiz, new questions added Aug 2026.
40 free House M.D. trivia questions with answers. House M.D. was the most-watched TV show on Earth in 2008, and this quiz treats it accordingly. Forty questions cover Dr. Gregory House and his team at Princeton-Plainsboro, the Sherlock Holmes homages hidden in plain sight, the Vicodin, the cane, the whiteboard, the guest villains, the bus crash, the psychiatric hospital, the prison, and the finale that sent House and Wilson off on motorcycles. It starts with House MD trivia any fan can answer and works up to the production stories: the audition tape shot in a hotel bathroom, the director who thought Hugh Laurie was American, and why Kutner had to die. Difficulty ratings are shown so you can pick your battles. Every answer was checked against Wikipedia's articles on the series, its characters and episodes, and each question carries its source.
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Q 01On which network did House air from 2004 to 2012?
Fox
It ran for eight seasons and 177 episodes, ending on May 21, 2012.
Q 02Who created House?
David Shore
Paul Attanasio had pitched a CSI-style medical detective show in which the germs were the suspects; Shore gave it a misanthropic hero.
Q 03At which fictional New Jersey institution is House set?
Princeton-Plainsboro
The pilot was shot in Vancouver; every later episode was filmed on the Fox lot in Century City, Los Angeles.
Q 04What is House's medical double specialty?
Infectious disease and nephrology
He introduces himself as a board-certified diagnostician and heads the hospital's Department of Diagnostic Medicine.
Q 05Which painkiller is House dependent on?
Vicodin
The season eight premiere is titled Twenty Vicodin, after the stash he needs to get through his last days in prison.
Q 06What caused the damage to House's right leg?
An infarction in his thigh muscle
An aneurysm in his thigh clotted during a game of golf; misdiagnosis let the muscle die, and Stacy authorised surgery he did not want.
Q 07What is the address of House's apartment, a nod to Sherlock Holmes?
221B Baker
The show's creator called House's own name a subtle homage to Holmes; Wilson is his Watson.
Q 08Under what name is the gunman who shoots House in the season two finale credited?
Moriarty
The episode is No Reason, and most of it turns out to be a hallucination House has while unconscious.
Q 09Which department does House's only real friend, Dr. James Wilson, head?
Oncology
Robert Sean Leonard plays him; the friendship echoes Holmes and Watson and carries the whole final episode.
Q 10What is Dr. Lisa Cuddy's job at the hospital?
Dean of Medicine
Lisa Edelstein's endocrinologist-turned-administrator left the show after season seven when a salary cut was proposed.
Q 11Which member of House's original team is a neurologist?
Foreman
Omar Epps's character had a juvenile record for burglary, which is partly why House hired him; he ends the series as Dean of Medicine.
Q 12Which actress plays immunologist Dr. Allison Cameron?
Jennifer Morrison
She later starred in Once Upon a Time; Jesse Spencer, who plays Chase, moved on to Chicago Fire.
Q 13Which genetic condition does Thirteen inherit from her mother?
Huntington's
Olivia Wilde's Dr. Remy Hadley got her nickname from her number in the season-four hiring contest.
Q 21Which episode drew the show's biggest audience, 29 million, after airing straight after Super Bowl XLII?
Frozen
Mira Sorvino guest-starred as a psychiatrist trapped at the South Pole; House diagnoses her over a video link.
Q 22Which billionaire, played by Chi McBride, tries to fire House in season one?
Edward Vogler
The pharmaceutical mogul appears in five episodes before the board chooses House over his money.
Q 23Why does Detective Michael Tritter, played by David Morse, pursue the doctor in season three?
He was left with a rectal thermometer
Q 14Why was Dr. Kutner written out of the show in season five?
Kal Penn joined the Obama White House
The character is found dead of a self-inflicted gunshot in the episode Simple Explanation, and returns as a hallucination in the finale.
Q 15Which member of the later team is a former plastic surgeon?
Taub
Peter Jacobson's character keeps a wife, a mistress and two babies born weeks apart, which House finds endlessly useful.
Q 16How did House recruit his new team in season four?
Through a reality-show style elimination contest
He starts with 40 applicants and numbers them rather than learning names; the show called it its own version of Survivor.
Q 17Which Massive Attack song is the show's opening theme in the United States?
Teardrop
It was chosen because its tempo mimics a heartbeat; rights issues meant many European broadcasts used different music.
Q 18Where did Hugh Laurie record his audition tape for House?
A hotel bathroom in Namibia
He was filming Flight of the Phoenix at the time and apologised for the poor lighting.
Q 19Which director of the pilot did not realise Hugh Laurie was English?
Bryan Singer
Singer had reportedly said he wanted an American for the part; Laurie credits his accent to a misspent youth watching too many movies.
Q 20In which year was House the most-watched television programme in the world?
2008
It was distributed to 71 countries; season three had averaged 19.4 million US viewers.
The vendetta ends with House in court over forged prescriptions and Cuddy perjuring herself to save him.
Q 24Which actress plays Stacy Warner, House's ex-girlfriend, in seasons one and two?
Sela Ward
She authorised the leg surgery that ended their relationship, then returns as the hospital's lawyer.
Q 25How does Amber Volakis, Wilson's girlfriend, die in the season four finale?
A bus crash
House was on the same bus and cannot remember why; the two-parter is House's Head and Wilson's Heart.
Q 26Where does House spend the two-hour season six premiere, Broken?
A psychiatric hospital
He checks into Mayfield to detox from Vicodin after hallucinating Amber and Kutner throughout season five.
Q 27What does House do to Cuddy's home in the season seven finale?
Drives his car into her living room
Cuddy had ended their relationship over his addiction; the stunt lands House in prison at the start of season eight.
Q 28Where is House at the start of season eight?
In prison
The premiere is titled Twenty Vicodin, and Foreman, now Dean of Medicine, gets him out.
Q 29Which team member takes over as head of the hospital in the final season?
Foreman
Chase ends the series running the Department of Diagnostic Medicine that House left behind.
Q 30What is the title of the series finale?
Everybody Dies
David Shore directed it as a bookend to the pilot's alternate title, Everybody Lies; Swan Song was the retrospective shown just before it.