Nurse Jackie
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50 free Nurse Jackie trivia questions with answers — trivia quiz, new questions added Oct 2026.
Nurse Jackie ran for seven seasons and gave television one of its most complicated lead characters: Jackie Peyton, a brilliant emergency room nurse who lies to almost everyone she loves. The show was praised for its acting and for an unsentimental picture of addiction, and viewers still argue about how it ended. This quiz covers the whole run: the staff of All Saints Hospital, Jackie's family and her secrets, the guest stars and directors, the awards, and the story of how the series was developed. It opens with things most viewers remember and works up to details only repeat watchers will know. It is for anyone who watched Zoey grow up, rolled their eyes at Coop, or wondered how much Akalitus really knew. Every answer comes with a short explanation, so you pick up something about the show even when you miss one.
30 of 50 questions with answers and explanations. Play the quiz
Q 01Edie Falco came to Nurse Jackie having already won three lead-actress Emmys for which HBO drama?
The Sopranos
The Sopranos made Edie Falco famous as Carmela, wife of the mob boss at its centre. She first passed on the nurse role, though the character intrigued her.
Q 02Which cable network aired Nurse Jackie, whose premiere was then the channel's most successful ever?
Showtime
Showtime pulled in a million viewers for the first episode and ordered a second season at once. The series went on to run for seven seasons.
Q 03Which drug does Jackie Peyton snort at the hospital's farewell party in Nurse Jackie's finale?
Heroin
Heroin, lifted from the belongings of a patient she treated that day, floors Jackie in the middle of the party. She had only just won her nursing license back.
Q 04Wendy & Lisa, who wrote Nurse Jackie's Emmy-winning theme music, rose to fame in which star's band?
Prince
Prince had Wendy Melvoin and Lisa Coleman in his band the Revolution, the group behind Purple Rain. Their Nurse Jackie theme won the 2010 Emmy for main title music.
Q 05What does Jackie's husband Kevin run in Nurse Jackie, the place where her lover Eddie befriends him?
A bar
A bar is Kevin's livelihood, and Eddie uses it: after learning Jackie is married, he starts drinking there and builds a friendship with her husband.
Q 06Whose visit does Nurse Jackie's Gloria Akalitus chase for All Saints with an anti-obesity campaign?
Michelle Obama
Michelle Obama, then First Lady, was the prize: Akalitus rallied the staff against childhood obesity to earn an official visit, only to get bad news about it later in the season.
Q 07Edie Falco won a 2010 Emmy for Nurse Jackie in which category, then said the label didn't suit her?
Comedy series
Comedy series was the Emmy slot for a show about addiction, and Edie Falco used her speech to say she isn't funny. Some critics then called for a separate dramedy category.
Q 08In Nurse Jackie's final season, what do Norwegian developers plan to turn All Saints Hospital into?
Luxury condos
Luxury condos are what the building becomes, and the nurses' protests and walkout can't block the sale. A newspaper report on the plan only sped the deal up.
Q 09Which actor, Carlisle Cullen in the Twilight films, plays cocky Dr. Fitch Cooper in Nurse Jackie?
Peter Facinelli
Peter Facinelli played 'Coop', billed as a likable golden boy whose calm front hides a nervous disposition. He leaves the hospital for a new job partway through the final season.
Q 10Which Reservoir Dogs actor directed Nurse Jackie episodes featuring his own younger brother?
Steve Buscemi
Steve Buscemi directed episodes in the first and third seasons. His younger brother Michael recurred as a troubled man living across the street from the hospital.
Q 11In which city is All Saints, the fictional hospital where Jackie Peyton works in Nurse Jackie, located?
New York
New York is home to All Saints, a Manhattan emergency room. The setting brings in local faces: TV news anchor Pat Kiernan turns up as a patient in the sixth season.
Q 12To which city does Dr. Eleanor O'Hara move in Nurse Jackie's fifth season to raise her baby son?
London
London takes away Jackie's closest ally just as she struggles to stay clean. O'Hara comes back for the finale and confronts Jackie about using again.
Q 13In early Nurse Jackie, which condition leads a school nurse to suggest medication for Jackie's daughter Grace?
Anxiety
Anxiety builds in Grace until she is pulling her hair out from stress, and Jackie bristles at the idea of pills for her. Later Jackie raids Grace's own prescription to feed her habit.
Q 21Paul Feig directed most of Nurse Jackie's second season shortly before making which hit 2011 film?
Bridesmaids
Bridesmaids made Paul Feig a star director soon after he directed eight of the show's twelve second-season episodes. He had earlier created Freaks and Geeks.
Q 22In Nurse Jackie's pilot, what does Jackie flush away to punish a violent man with diplomatic immunity?
His severed ear
His severed ear goes down the toilet as Jackie's own rough justice. It resurfaces an episode later, when Zoey finds it and hands it to the hospital administrator.
Q 23With what does Jackie break her own finger in Nurse Jackie to hide that her wedding ring was sawn off?
A hammer
Q 14What do Jackie's husband Kevin and Dr. O'Hara stage at her home in Nurse Jackie's second-season finale?
An intervention
An intervention awaits Jackie after Kevin finds her secret credit card bill for prescriptions. She denies being an addict and insists the spending was for their daughters.
Q 15How does Nurse Jackie's final scene leave Jackie Peyton after she overdoses at the hospital's goodbye party?
Her fate is unresolved
Her fate is unresolved on purpose: showrunner Clyde Phillips said the writers wanted viewers to keep debating the ending once the show was over.
Q 16What is the job of Frank Verelli, the man Jackie dates after her divorce in Nurse Jackie's fifth season?
A police officer
A police officer, Frank meets Jackie while investigating the crash she causes on her way out of divorce court. He takes it in stride when she tells him about her history of addiction.
Q 17Caryn Mandabach, the producer who first conceived Nurse Jackie, went on to make which British period drama?
Peaky Blinders
Peaky Blinders is owned and produced by Caryn Mandabach, who made her name on American sitcoms such as Roseanne. Her hospital series began with stories an ER nurse told her.
Q 18Which actor joins Nurse Jackie's final season as the ER doctor with a brain tumor who replaces Coop?
Tony Shalhoub
Tony Shalhoub plays Dr. Bernard, who bonds with Jackie and speaks up for her at her license hearing. He had already won three Emmys as the detective Adrian Monk.
Q 19Which actor plays hospital boss Dr. Mike Cruz in Nurse Jackie's fourth season, opposite his real-life son?
Bobby Cannavale
Bobby Cannavale earned two Emmy nominations as the corporate administrator who fires Jackie. His son Jake played Cruz's son Charlie, the young addict Jackie befriends in rehab.
Q 20Which actress, later a wrestler in GLOW, plays first-year resident Dr. Carrie Roman in Nurse Jackie?
Betty Gilpin
Betty Gilpin joined in the fifth season as a resident skating by on her looks. GLOW, where she played Liberty Belle, later brought her three Emmy nominations.
A hammer does the job after Dr. O'Hara cuts the stuck ring off with a bone saw at work. Jackie needs an injury to explain the missing ring to Kevin.
Q 24What does Jackie forge for a dead bike messenger in Nurse Jackie's pilot, trying to make good of his death?
An organ donor card
An organ donor card, forged in the dead man's name, is Jackie's way of salvaging something from a death caused by Coop's negligence. Coop later threatens to report her over a fake donor card.
Q 25Who raised Nurse Jackie's Dr. Fitch Cooper, as viewers learn when a gallbladder attack brings family to the ER?
Two mothers
Two mothers, played by Blythe Danner and Swoosie Kurtz, arrive when one of them needs treatment. Their later divorce sends Coop into a depression in the third season.
Q 26Which condition lies behind Dr. Fitch Cooper involuntarily touching colleagues' breasts in Nurse Jackie?
Tourette syndrome
Tourette syndrome troubled Coop as a child, he confides. It earns him a punch from Zoey's boyfriend Lenny, who sees the touching and knows nothing of the diagnosis.
Q 27What does the man who shouts from an apartment window opposite All Saints call himself in Nurse Jackie?
God
God is a mentally ill neighbour who becomes a recurring presence. Zoey later treats him, talks him through an identity crisis and confides in him about her love life.
Q 28What does Gloria Akalitus accidentally use on herself after finding it lying in a hallway in Nurse Jackie?
A Taser
A Taser left unattended in the corridor gets the better of the stern administrator, who had been fuming about the staff's disregard for order and professionalism.
Q 29What replaces pharmacist Eddie Walzer at All Saints Hospital late in Nurse Jackie's first season?
A pill-dispensing machine
A pill-dispensing machine called the Pill-O-Matix takes over, and it proves so frustrating that Gloria Akalitus invites Eddie back the following season.
Q 30Which social network does Dr. Fitch Cooper take up as a way to vent in Nurse Jackie's second season?
Twitter gives Coop an outlet in an episode named after it, to Jackie's irritation. That season he also lands on a magazine's list of top doctors and fronts the hospital's ads.